Unraveling the Inconsistencies of Cardiac Differentiation Efficiency Induced by the GSK3β Inhibitor CHIR99021 in Human Pluripotent Stem Cells

Cardiac differentiation efficiency is hampered by inconsistencies and low reproducibility. We analyzed the differentiation process of multiple human pluripotent stem cell (hPSC) lines in response to dynamic GSK3β inhibition under varying cell culture conditions. hPSCs showed strong differences in ce...

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Vydáno v:Stem Cell Reports
Hlavní autoři: Laco, Filip, Woo, Tsung Liang, Zhong, Qixing, Szmyd, Radoslaw, Ting, Sherwin, Khan, Fahima Jaleel, Chai, Christina L.L., Reuveny, Shaul, Chen, Allen, Oh, Steve
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5989659/
https://ncbi.nlm.nih.gov/pubmed/29706502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2018.03.023
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