Unraveling the Inconsistencies of Cardiac Differentiation Efficiency Induced by the GSK3β Inhibitor CHIR99021 in Human Pluripotent Stem Cells

Cardiac differentiation efficiency is hampered by inconsistencies and low reproducibility. We analyzed the differentiation process of multiple human pluripotent stem cell (hPSC) lines in response to dynamic GSK3β inhibition under varying cell culture conditions. hPSCs showed strong differences in ce...

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Publicado en:Stem Cell Reports
Autores principales: Laco, Filip, Woo, Tsung Liang, Zhong, Qixing, Szmyd, Radoslaw, Ting, Sherwin, Khan, Fahima Jaleel, Chai, Christina L.L., Reuveny, Shaul, Chen, Allen, Oh, Steve
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5989659/
https://ncbi.nlm.nih.gov/pubmed/29706502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2018.03.023
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