Structure-Based Analysis of Boronic Acids as Inhibitors of Acinetobacter-Derived Cephalosporinase-7, a Unique Class C β-Lactamase

Acinetobacter baumannii is a multidrug resistant pathogen that infects more than 12 000 patients each year in the US. Much of the resistance to β-lactam antibiotics in Acinetobacter spp. is mediated by class C β-lactamases known as Acinetobacter-derived cephalosporinases (ADCs). ADCs are unaffected...

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Detalhes bibliográficos
Publicado no:ACS Infect Dis
Main Authors: Bouza, Alexandra A., Swanson, Hollister C., Smolen, Kali A., VanDine, Alison L., Taracila, Magdalena A., Romagnoli, Chiara, Caselli, Emilia, Prati, Fabio, Bonomo, Robert A., Powers, Rachel A., Wallar, Bradley J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5981863/
https://ncbi.nlm.nih.gov/pubmed/29144724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.7b00152
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