Biochemical and Structural Analysis of Inhibitors Targeting the ADC-7 Cephalosporinase of Acinetobacter baumannii

[Image: see text] β-Lactam resistance in Acinetobacter baumannii presents one of the greatest challenges to contemporary antimicrobial chemotherapy. Much of this resistance to cephalosporins derives from the expression of the class C β-lactamase enzymes, known as Acinetobacter-derived cephalosporina...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Powers, Rachel A., Swanson, Hollister C., Taracila, Magdalena A., Florek, Nicholas W., Romagnoli, Chiara, Caselli, Emilia, Prati, Fabio, Bonomo, Robert A., Wallar, Bradley J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4263437/
https://ncbi.nlm.nih.gov/pubmed/25380506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi500887n
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