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4-Hydroxypiperidines and Their Flexible 3-(Amino)propyloxy Analogues as Non-Imidazole Histamine H(3) Receptor Antagonist: Further Structure–Activity Relationship Exploration and In Vitro and In Vivo Pharmacological Evaluation
Presynaptic histamine H(3) receptors (H(3)R) act as auto- or heteroreceptors controlling, respectively, the release of histamine and of other neurotransmitters in the central nervous system (CNS). The extracellular levels of several neurotransmitters are enhanced by H(3)R antagonists, and there is a...
Zapisane w:
| Wydane w: | Int J Mol Sci |
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| Główni autorzy: | , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
MDPI
2018
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5979327/ https://ncbi.nlm.nih.gov/pubmed/29671795 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19041243 |
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