Non-Imidazole Histamine H(3) Ligands. Part VII. Synthesis, In Vitro and In Vivo Characterization of 5-Substituted-2-thiazol-4-n-propylpiperazines

H(3) receptors present on histaminergic and non-histaminergic neurons, act as autoreceptors or heteroreceptors controlling neurotransmitter release and synthesis. Previous, studies have found that the compound N-methyl-N-3-phenylalkyl-2-[2-(4-n-propylpiperazin-1-yl)-1,3-thiazol-5-yl]ethan-1-amine (A...

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Publicado en:Molecules
Main Authors: Guryn, Roman, Staszewski, Marek, Stasiak, Anna, McNaught Flores, Daniel, Fogel, Wiesława Agnieszka, Leurs, Rob, Walczyński, Krzysztof
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6017745/
https://ncbi.nlm.nih.gov/pubmed/29401659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23020326
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