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Modulation of histamine H(2) receptor signalling by G-protein-coupled receptor kinase 2 and 3
1. To evaluate the role of G-protein-coupled receptor kinases (GRK) in the desensitization of the histamine H(2) receptor, the H(2) receptor was transiently cotransfected with GRK2, 3, 5 or 6 in COS-7 cells and the cyclic AMP levels in response to histamine were studied. 2. Coexpression of the H(2)...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2000
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1572484/ https://ncbi.nlm.nih.gov/pubmed/11139450 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703676 |
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