MIG-6 suppresses endometrial epithelial cell proliferation by inhibiting phospho-AKT

BACKGROUND: Aberrant hyperactivation of epithelial proliferation, AKT signaling, and association with unopposed estrogen (E2) exposure is the most common endometrial cancer dysfunction. In the normal uterus, progesterone (P4) inhibits proliferation by coordinating stromal-epithelial cross-talk, whic...

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Bibliographic Details
Published in:BMC Cancer
Main Authors: Yoo, Jung-Yoon, Kang, Hee-Bum, Broaddus, Russell R., Risinger, John I., Choi, Kyung-Chul, Kim, Tae Hoon
Format: Artigo
Language:Inglês
Published: BioMed Central 2018
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5975686/
https://ncbi.nlm.nih.gov/pubmed/29843645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4502-7
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