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Critical tumor suppressor function mediated by epithelial Mig-6 in endometrial cancer

Endometrial cancer is preceded by endometrial hyperplasia, unopposed estrogen exposure and genetic alterations, but the precise causes of endometrial cancer remain uncertain. Mig-6, mainly known as a negative regulator of the EGF receptor, is an important mediator of progesterone signaling in the ut...

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Hlavní autoři: Kim, Tae Hoon, Lee, Dong-Kee, Cho, Sung-Nam, Orvis, Grant D., Behringer, Richard R., Lydon, John P., Ku, Bon Jeong, McCampbell, Adrienne S., Broaddus, Russell R., Jeong, Jae-Wook
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3745525/
https://ncbi.nlm.nih.gov/pubmed/23811943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-0241
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