Mig-6 suppresses endometrial cancer associated with Pten deficiency and ERK activation

PTEN mutations are the most common genetic alterations in endometrial cancer. Loss of PTEN and subsequent AKT activation stimulate ERα-dependent pathways that play an important role in endometrial tumorigenesis. The major pathologic phenomenon of endometrial cancer is the loss of ovarian steroid hor...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Kim, Tae Hoon, Yoo, Jung-Yoon, Kim, Hong Im, Gilbert, Jenifer, Ku, Bon Jeong, Li, Jane, Mills, Gordon B., Broaddus, Russell R., Lydon, John P., Lim, Jeong Mook, Yoon, Ho-Geun, Jeong, Jae-Wook
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4268053/
https://ncbi.nlm.nih.gov/pubmed/25377472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-0794
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