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The synergistic effect of Mig-6 and Pten ablation on endometrial cancer development and progression

Ablation of Mig-6 in the murine uterus leads to the development of endometrial hyperplasia and estrogen-induced endometrial cancer. An additional endometrial cancer mouse model is generated by ablation of Pten (either as heterozygotes or by conditional uterine ablation). To determine the interplay b...

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Autors principals: Kim, Tae Hoon, Franco, Heather L., Jung, Sung Yun, Qin, Jun, Broaddus, Russell R., Lydon, John P., Jeong, Jae-Wook
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4013686/
https://ncbi.nlm.nih.gov/pubmed/20418913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.126
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