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MIG-6 suppresses endometrial epithelial cell proliferation by inhibiting phospho-AKT

BACKGROUND: Aberrant hyperactivation of epithelial proliferation, AKT signaling, and association with unopposed estrogen (E2) exposure is the most common endometrial cancer dysfunction. In the normal uterus, progesterone (P4) inhibits proliferation by coordinating stromal-epithelial cross-talk, whic...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Yoo, Jung-Yoon, Kang, Hee-Bum, Broaddus, Russell R., Risinger, John I., Choi, Kyung-Chul, Kim, Tae Hoon
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5975686/
https://ncbi.nlm.nih.gov/pubmed/29843645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4502-7
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