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Subchronic administration of (R,S)-ketamine induces ketamine ring hydroxylation in Wistar rats
Subchronic administration of (R,S)-ketamine, (R,S)-Ket, is used in the treatment of neuropathic pain, in particular Complex Regional Pain Syndrome, but the effect of this protocol on the metabolism of (R,S)-Ket is unknown. In this study, daily administration of a low dose of (R,S)-Ket for 14-days to...
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| 出版年: | J Pharm Biomed Anal |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5972519/ https://ncbi.nlm.nih.gov/pubmed/27017097 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpba.2016.03.030 |
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