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Phosphoramidates and phosphonamidates (ProTides) with antiviral activity

Following the first report on the nucleoside phosphoramidate (ProTide) prodrug approach in 1990 by Chris McGuigan, the extensive investigation of ProTide technology has begun in many laboratories. Designed with aim to overcome limitations and the key resistance mechanisms associated with nucleoside...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Antivir Chem Chemother
Hauptverfasser: Slusarczyk, Magdalena, Serpi, Michaela, Pertusati, Fabrizio
Format: Artigo
Sprache:Inglês
Veröffentlicht: SAGE Publications 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5971382/
https://ncbi.nlm.nih.gov/pubmed/29792071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2040206618775243
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