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Anchimerically Activatable Antiviral ProTides
[Image: see text] This work describes the synthesis and biological evaluation of an anchimerically activated proTide of 2′-C-β-methylguanosine as an inhibitor of dengue virus 2 (DENV-2). The proTide incorporates a chemically cleavable 2-(methylthio)ethyl moiety and a HINT1 hydrolyzable tryptamine ph...
Gardado en:
| Publicado en: | ACS Med Chem Lett |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Chemical
Society
2017
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5601376/ https://ncbi.nlm.nih.gov/pubmed/28947944 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.7b00277 |
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