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The ProTides Boom

The masking of nucleoside phosphate and phosphonate groups by an aryl motif and an amino acid ester, nowadays known as the ‘ProTide’ technology, has proven to be effective in the discovery of nucleotide therapeutics. Indeed, this technology, which was invented by Chris McGuigan in the early 1990s, h...

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Detalhes bibliográficos
Publicado no:ChemMedChem
Autor principal: Mehellou, Youcef
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7162417/
https://ncbi.nlm.nih.gov/pubmed/27159529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201600156
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