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The ProTides Boom

The masking of nucleoside phosphate and phosphonate groups by an aryl motif and an amino acid ester, nowadays known as the ‘ProTide’ technology, has proven to be effective in the discovery of nucleotide therapeutics. Indeed, this technology, which was invented by Chris McGuigan in the early 1990s, h...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:ChemMedChem
1. Verfasser: Mehellou, Youcef
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7162417/
https://ncbi.nlm.nih.gov/pubmed/27159529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201600156
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