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Phosphoramidates and phosphonamidates (ProTides) with antiviral activity

Following the first report on the nucleoside phosphoramidate (ProTide) prodrug approach in 1990 by Chris McGuigan, the extensive investigation of ProTide technology has begun in many laboratories. Designed with aim to overcome limitations and the key resistance mechanisms associated with nucleoside...

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Detalhes bibliográficos
Publicado no:Antivir Chem Chemother
Main Authors: Slusarczyk, Magdalena, Serpi, Michaela, Pertusati, Fabrizio
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5971382/
https://ncbi.nlm.nih.gov/pubmed/29792071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2040206618775243
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