Stapled peptides as a new technology to investigate protein–protein interactions in human platelets

Platelets are blood cells with numerous crucial pathophysiological roles in hemostasis, cardiovascular thrombotic events and cancer metastasis. Platelet activation requires the engagement of intracellular signalling pathways that involve protein–protein interactions (PPIs). A better understanding of...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Iegre, Jessica, Ahmed, Niaz S., Gaynord, Josephine S., Wu, Yuteng, Herlihy, Kara M., Tan, Yaw Sing, Lopes-Pires, Maria E., Jha, Rupam, Lau, Yu Heng, Sore, Hannah F., Verma, Chandra, O' Donovan, Daniel H., Pugh, Nicholas, Spring, David R.
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2018
Assuntos:
Chemistry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5969508/
https://ncbi.nlm.nih.gov/pubmed/29899957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc00284c
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