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Development of a Multifunctional Benzophenone Linker for Peptide Stapling and Photoaffinity Labelling

Photoaffinity labelling is a useful method for studying how proteins interact with ligands and biomolecules, and can help identify and characterise new targets for the development of new therapeutics. We present the design and synthesis of a novel multifunctional benzophenone linker that serves as b...

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Bibliographische Detailangaben
Veröffentlicht in:Chembiochem
Hauptverfasser: Wu, Yuteng, Olsen, Lasse B., Lau, Yu Heng, Jensen, Claus Hatt, Rossmann, Maxim, Baker, Ysobel R., Sore, Hannah F., Collins, Súil, Spring, David R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862033/
https://ncbi.nlm.nih.gov/pubmed/26919579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201500648
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