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Development of a Multifunctional Benzophenone Linker for Peptide Stapling and Photoaffinity Labelling

Photoaffinity labelling is a useful method for studying how proteins interact with ligands and biomolecules, and can help identify and characterise new targets for the development of new therapeutics. We present the design and synthesis of a novel multifunctional benzophenone linker that serves as b...

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Detalles Bibliográficos
Publicado en:Chembiochem
Autores principales: Wu, Yuteng, Olsen, Lasse B., Lau, Yu Heng, Jensen, Claus Hatt, Rossmann, Maxim, Baker, Ysobel R., Sore, Hannah F., Collins, Súil, Spring, David R.
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862033/
https://ncbi.nlm.nih.gov/pubmed/26919579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201500648
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