Using Ligand-Mapping Simulations to Design a Ligand Selectively Targeting a Cryptic Surface Pocket of Polo-Like Kinase 1**

Por Tan, Yaw Sing, Śledź, Paweł, Lang, Steffen, Stubbs, Christopher J, Spring, David R, Abell, Chris, Best, Robert B
Publicado em 2012

Functional characterization of p53 pathway components in the ancient metazoan Trichoplax adhaerens

Por Siau, Jia Wei, Coffill, Cynthia R., Zhang, Weiyun Villien, Tan, Yaw Sing, Hundt, Juliane, Lane, David, Verma, Chandra, Ghadessy, Farid
Publicado no Sci Rep (2016)

Macrocyclized Extended Peptides: Inhibiting the Substrate-Recognition Domain of Tankyrase

Por Xu, Wenshu, Lau, Yu Heng, Fischer, Gerhard, Tan, Yaw Sing, Chattopadhyay, Anasuya, de la Roche, Marc, Hyvönen, Marko, Verma, Chandra, Spring, David R., Itzhaki, Laura S.
Publicado no J Am Chem Soc (2017)

Development of Cell‐Permeable, Non‐Helical Constrained Peptides to Target a Key Protein–Protein Interaction in Ovarian Cancer

Por Wiedmann, Mareike M., Tan, Yaw Sing, Wu, Yuteng, Aibara, Shintaro, Xu, Wenshu, Sore, Hannah F., Verma, Chandra S., Itzhaki, Laura, Stewart, Murray, Brenton, James D., Spring, David R.
Publicado no Angew Chem Int Ed Engl (2016)

A diversity-oriented synthesis strategy enabling the combinatorial-type variation of macrocyclic peptidomimetic scaffolds

Por Isidro-Llobet, Albert, Hadje Georgiou, Kathy, Galloway, Warren R. J. D., Giacomini, Elisa, Hansen, Mette R., Méndez-Abt, Gabriela, Tan, Yaw Sing, Carro, Laura, Sore, Hannah F., Spring, David R.
Publicado no Org Biomol Chem (2015)

Discovery of a small-molecule binder of the oncoprotein gankyrin that modulates gankyrin activity in the cell

Por Chattopadhyay, Anasuya, O’Connor, Cornelius J., Zhang, Fengzhi, Galvagnion, Celine, Galloway, Warren R. J. D., Tan, Yaw Sing, Stokes, Jamie E., Rahman, Taufiq, Verma, Chandra, Spring, David R., Itzhaki, Laura S.
Publicado no Sci Rep (2016)

The p53–Mdm2 interaction and the E3 ligase activity of Mdm2/Mdm4 are conserved from lampreys to humans

Por Coffill, Cynthia R., Lee, Alison P., Siau, Jia Wei, Chee, Sharon M., Joseph, Thomas L., Tan, Yaw Sing, Madhumalar, Arumugam, Tay, Boon-Hui, Brenner, Sydney, Verma, Chandra S., Ghadessy, Farid J., Venkatesh, Byrappa, Lane, David P.
Publicado no Genes Dev (2016)