The p53–Mdm2 interaction and the E3 ligase activity of Mdm2/Mdm4 are conserved from lampreys to humans

The extant jawless vertebrates, represented by lampreys and hagfish, are the oldest group of vertebrates and provide an interesting genomic evolutionary pivot point between invertebrates and jawed vertebrates. Through genome analysis of one of these jawless vertebrates, the Japanese lamprey (Lethent...

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Dades bibliogràfiques
Publicat a:Genes Dev
Autors principals: Coffill, Cynthia R., Lee, Alison P., Siau, Jia Wei, Chee, Sharon M., Joseph, Thomas L., Tan, Yaw Sing, Madhumalar, Arumugam, Tay, Boon-Hui, Brenner, Sydney, Verma, Chandra S., Ghadessy, Farid J., Venkatesh, Byrappa, Lane, David P.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2016
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4743058/
https://ncbi.nlm.nih.gov/pubmed/26798135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.274118.115
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