A diversity-oriented synthesis strategy enabling the combinatorial-type variation of macrocyclic peptidomimetic scaffolds

Macrocyclic peptidomimetics are associated with a broad range of biological activities. However, despite such potentially valuable properties, the macrocyclic peptidomimetic structural class is generally considered as being poorly explored within drug discovery. This has been attributed to the lack...

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Detalhes bibliográficos
Publicado no:Org Biomol Chem
Main Authors: Isidro-Llobet, Albert, Hadje Georgiou, Kathy, Galloway, Warren R. J. D., Giacomini, Elisa, Hansen, Mette R., Méndez-Abt, Gabriela, Tan, Yaw Sing, Carro, Laura, Sore, Hannah F., Spring, David R.
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2015
Assuntos:
Chemistry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4441267/
https://ncbi.nlm.nih.gov/pubmed/25778821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5ob00371g
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