AIRE promotes androgen-independent prostate cancer by directly regulating IL-6 and modulating tumor microenvironment

Early stage prostate cancers are dependent on androgens for their growth and survival and androgen withdrawal causes them to regress. Progressive prostate cancers eventually acquire androgen independence rendering anti-androgen therapy ineffective. However, the factors leading to this have not been...

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Bibliografski detalji
Izdano u:Oncogenesis
Glavni autori: Kalra, Rashi, Bhagyaraj, Ella, Tiwari, Drishti, Nanduri, Ravikanth, Chacko, Anuja P., Jain, Monika, Mahajan, Sahil, Khatri, Neeraj, Gupta, Pawan
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5968032/
https://ncbi.nlm.nih.gov/pubmed/29795364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-018-0053-7
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