AIRE promotes androgen-independent prostate cancer by directly regulating IL-6 and modulating tumor microenvironment

Early stage prostate cancers are dependent on androgens for their growth and survival and androgen withdrawal causes them to regress. Progressive prostate cancers eventually acquire androgen independence rendering anti-androgen therapy ineffective. However, the factors leading to this have not been...

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Vydáno v:Oncogenesis
Hlavní autoři: Kalra, Rashi, Bhagyaraj, Ella, Tiwari, Drishti, Nanduri, Ravikanth, Chacko, Anuja P., Jain, Monika, Mahajan, Sahil, Khatri, Neeraj, Gupta, Pawan
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5968032/
https://ncbi.nlm.nih.gov/pubmed/29795364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-018-0053-7
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