TGF-β induced chemoresistance in liver cancer is modulated by xenobiotic nuclear receptor PXR

Hepatocellular carcinoma appears as an extremely angiogenic solid tumor marked by apoptosis evasion, dysregulated cell cycle and low sensitivity to chemotherapy. TGF-β, a multifunctional cytokine, plays a pleiotropic role in the tumor microenvironment and has implications in cancer drug resistance....

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Vydáno v:Cell Cycle
Hlavní autoři: Bhagyaraj, Ella, Ahuja, Nancy, Kumar, Sumit, Tiwari, Drishti, Gupta, Shalini, Nanduri, Ravikanth, Gupta, Pawan
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2019
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6927732/
https://ncbi.nlm.nih.gov/pubmed/31739702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2019.1693120
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