TGF-β induced chemoresistance in liver cancer is modulated by xenobiotic nuclear receptor PXR

Hepatocellular carcinoma appears as an extremely angiogenic solid tumor marked by apoptosis evasion, dysregulated cell cycle and low sensitivity to chemotherapy. TGF-β, a multifunctional cytokine, plays a pleiotropic role in the tumor microenvironment and has implications in cancer drug resistance....

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Dades bibliogràfiques
Publicat a:Cell Cycle
Autors principals: Bhagyaraj, Ella, Ahuja, Nancy, Kumar, Sumit, Tiwari, Drishti, Gupta, Shalini, Nanduri, Ravikanth, Gupta, Pawan
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2019
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6927732/
https://ncbi.nlm.nih.gov/pubmed/31739702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2019.1693120
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