A human xenobiotic nuclear receptor contributes to nonresponsiveness of Mycobacterium tuberculosis to the antituberculosis drug rifampicin

Mycobacterium tuberculosis is the causative agent of tuberculosis (TB). It acquires phenotypic drug resistance inside macrophages, and this resistance mainly arises from host-induced stress. However, whether cellular drug-efflux mechanisms in macrophages contribute to nonresponsiveness of M. tubercu...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Bhagyaraj, Ella, Tiwari, Drishti, Ahuja, Nancy, Nanduri, Ravikanth, Saini, Ankita, Kalra, Rashi, Kumar, Sumit, Janmeja, Ashok Kumar, Gupta, Pawan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5846149/
https://ncbi.nlm.nih.gov/pubmed/29358328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.818377
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