A human xenobiotic nuclear receptor contributes to nonresponsiveness of Mycobacterium tuberculosis to the antituberculosis drug rifampicin

Mycobacterium tuberculosis is the causative agent of tuberculosis (TB). It acquires phenotypic drug resistance inside macrophages, and this resistance mainly arises from host-induced stress. However, whether cellular drug-efflux mechanisms in macrophages contribute to nonresponsiveness of M. tubercu...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Bhagyaraj, Ella, Tiwari, Drishti, Ahuja, Nancy, Nanduri, Ravikanth, Saini, Ankita, Kalra, Rashi, Kumar, Sumit, Janmeja, Ashok Kumar, Gupta, Pawan
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2018
Matèries:
Cell Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5846149/
https://ncbi.nlm.nih.gov/pubmed/29358328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.818377
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