A human xenobiotic nuclear receptor contributes to nonresponsiveness of Mycobacterium tuberculosis to the antituberculosis drug rifampicin

Mycobacterium tuberculosis is the causative agent of tuberculosis (TB). It acquires phenotypic drug resistance inside macrophages, and this resistance mainly arises from host-induced stress. However, whether cellular drug-efflux mechanisms in macrophages contribute to nonresponsiveness of M. tubercu...

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Vydáno v:J Biol Chem
Hlavní autoři: Bhagyaraj, Ella, Tiwari, Drishti, Ahuja, Nancy, Nanduri, Ravikanth, Saini, Ankita, Kalra, Rashi, Kumar, Sumit, Janmeja, Ashok Kumar, Gupta, Pawan
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2018
Témata:
Cell Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5846149/
https://ncbi.nlm.nih.gov/pubmed/29358328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.818377
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