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TGF-β induced chemoresistance in liver cancer is modulated by xenobiotic nuclear receptor PXR
Hepatocellular carcinoma appears as an extremely angiogenic solid tumor marked by apoptosis evasion, dysregulated cell cycle and low sensitivity to chemotherapy. TGF-β, a multifunctional cytokine, plays a pleiotropic role in the tumor microenvironment and has implications in cancer drug resistance....
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| Publicado no: | Cell Cycle |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6927732/ https://ncbi.nlm.nih.gov/pubmed/31739702 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2019.1693120 |
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