TGF-β induced chemoresistance in liver cancer is modulated by xenobiotic nuclear receptor PXR

Hepatocellular carcinoma appears as an extremely angiogenic solid tumor marked by apoptosis evasion, dysregulated cell cycle and low sensitivity to chemotherapy. TGF-β, a multifunctional cytokine, plays a pleiotropic role in the tumor microenvironment and has implications in cancer drug resistance....

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Bibliografiske detaljer
Udgivet i:Cell Cycle
Main Authors: Bhagyaraj, Ella, Ahuja, Nancy, Kumar, Sumit, Tiwari, Drishti, Gupta, Shalini, Nanduri, Ravikanth, Gupta, Pawan
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2019
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6927732/
https://ncbi.nlm.nih.gov/pubmed/31739702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2019.1693120
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