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HUMAN LIVER MICROSOMES ATROPSELECTIVELY METABOLIZE 2,2′,3,4′,6-PENTACHLOROBIPHENYL (PCB 91) TO A 1,2-SHIFT PRODUCT AS THE MAJOR METABOLITE
Polychlorinated biphenlys (PCBs) and their hydroxylated metabolites (OH-PCBs) have been implicated in neurodevelopmental disorders. Several neurotoxic PCBs, such as PCB 91, are chiral because they form stable rotational isomers, or atropisomers, that are non-superimposable mirror images of each othe...
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| Publicado no: | Environ Sci Technol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5966832/ https://ncbi.nlm.nih.gov/pubmed/29659268 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.est.8b00612 |
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