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HUMAN LIVER MICROSOMES ATROPSELECTIVELY METABOLIZE 2,2′,3,4′,6-PENTACHLOROBIPHENYL (PCB 91) TO A 1,2-SHIFT PRODUCT AS THE MAJOR METABOLITE

Polychlorinated biphenlys (PCBs) and their hydroxylated metabolites (OH-PCBs) have been implicated in neurodevelopmental disorders. Several neurotoxic PCBs, such as PCB 91, are chiral because they form stable rotational isomers, or atropisomers, that are non-superimposable mirror images of each othe...

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Dades bibliogràfiques
Publicat a:Environ Sci Technol
Autors principals: Uwimana, Eric, Li, Xueshu, Lehmler, Hans-Joachim
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5966832/
https://ncbi.nlm.nih.gov/pubmed/29659268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.est.8b00612
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