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EFFECT OF PREGNANCY ON THE DISPOSITION OF 2,2′,3,5′,6-PENTACHLOROBIPHENYL (PCB 95) ATROPISOMERS AND THEIR HYDROXYLATED METABOLITES IN FEMALE MICE
Chiral PCBs, such as PCB 95, are developmental neurotoxicants that undergo atropisomeric enrichment in non-pregnant, adult mice. Because pregnancy is associated with changes in hepatic cytochrome P450 enzyme activity as well as lipid disposition and metabolism, this study investigates the effect of...
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| Publicado no: | Chem Res Toxicol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4579038/ https://ncbi.nlm.nih.gov/pubmed/26271003 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.5b00241 |
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