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EFFECT OF PREGNANCY ON THE DISPOSITION OF 2,2′,3,5′,6-PENTACHLOROBIPHENYL (PCB 95) ATROPISOMERS AND THEIR HYDROXYLATED METABOLITES IN FEMALE MICE

Chiral PCBs, such as PCB 95, are developmental neurotoxicants that undergo atropisomeric enrichment in non-pregnant, adult mice. Because pregnancy is associated with changes in hepatic cytochrome P450 enzyme activity as well as lipid disposition and metabolism, this study investigates the effect of...

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Bibliografiske detaljer
Udgivet i:Chem Res Toxicol
Main Authors: Kania-Korwel, Izabela, Barnhart, Christopher D., Lein, Pamela J., Lehmler, Hans-Joachim
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4579038/
https://ncbi.nlm.nih.gov/pubmed/26271003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.5b00241
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