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EFFECTS OF THIOL ANTIOXIDANTS ON THE ATROPSELECTIVE OXIDATION OF 2,2′,3,3′,6,6′-HEXACHLOROBIPHENYL (PCB 136) BY RAT LIVER MICROSOMES

Chiral polychlorinated biphenyl (PCB) congeners, such as PCB 136, are atropselectively metabolized to various hydroxylated PCB metabolites (HO-PCBs). The present study investigates the effect of two thiol antioxidants, glutathione and N-acetyl-cysteine (NAC), on profiles and chiral signatures of PCB...

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Detalhes bibliográficos
Publicado no:Environ Sci Pollut Res Int
Main Authors: Wu, Xianai, Lehmler, Hans-Joachim
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4706823/
https://ncbi.nlm.nih.gov/pubmed/26155892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11356-015-4987-4
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