Enantiomeric Specificity of (-)-2,2′,3,3′,6,6′-Hexachlorobiphenyl ((-)-PCB 136) Towards Ryanodine Receptor Types 1 and 2

Polychlorinated biphenyls (PCBs) with unsymmetrical chlorine substitutions and multiple ortho-substitutions that restrict rotation around the biphenyl bond may exist in two stable enantiomeric forms. Stereospecific binding and functional modification of specific biological signaling targets have not...

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Detalhes bibliográficos
Principais autores: Pessah, Isaac N., Lehmler, Hans-Joachim, Robertson, Larry W., Perez, Claudio F., Cabrales, Elaine, Bose, Diptiman D., Feng, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662366/
https://ncbi.nlm.nih.gov/pubmed/18954145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx800328u
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