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Hepatic Metabolism Affects the Atropselective Disposition of 2,2′,3,3′,6,6′-Hexachlorobiphenyl (PCB 136) in Mice

[Image: see text] To understand the role of hepatic vs extrahepatic metabolism in the disposition of chiral PCBs, we studied the disposition of 2,2′,3,3′,6,6′-hexachlorobiphenyl (PCB 136) and its hydroxylated metabolites (HO-PCBs) in mice with defective hepatic metabolism due to the liver-specific d...

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Detalhes bibliográficos
Publicado no:Environ Sci Technol
Main Authors: Wu, Xianai, Barnhart, Christopher, Lein, Pamela J., Lehmler, Hans-Joachim
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291784/
https://ncbi.nlm.nih.gov/pubmed/25420130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/es504766p
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