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Microsomal Oxidation of 2,2′,3,3′,6,6′-Hexachlorobiphenyl (PCB 136) Results in Species-Dependent Chiral Signatures of the Hydroxylated Metabolites

[Image: see text] Chiral polychlorinated biphenyls (PCBs) display variable atropisomeric enrichment in wildlife and animal models, especially at higher trophic levels. These differences in PCBs’ chiral signatures are, at least in part, due to species-dependent oxidation of PCBs to hydroxylated PCB m...

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Autores principales: Wu, Xianai, Kammerer, Austin, Lehmler, Hans-Joachim
Formato: Artigo
Lenguaje:Inglês
Publicado: American Chemical Society 2014
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3983324/
https://ncbi.nlm.nih.gov/pubmed/24467194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/es405433t
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