MitoNEET (CISD1) Knockout Mice Show Signs of Striatal Mitochondrial Dysfunction and a Parkinson’s Disease Phenotype

Mitochondrial dysfunction is thought to play a significant role in neurodegeneration observed in Parkinson’s disease (PD), yet the mechanisms underlying this pathology remain unclear. Here, we demonstrate that loss of mitoNEET (CISD1), an iron–sulfur containing protein that regulates mitochondrial b...

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Detalhes bibliográficos
Publicado no:ACS Chem Neurosci
Main Authors: Geldenhuys, Werner J., Benkovic, Stanley A., Lin, Li, Yonutas, Heather M., Crish, Samuel D., Sullivan, Patrick G., Darvesh, Altaf S., Brown, Candice M., Richardson, Jason R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5964979/
https://ncbi.nlm.nih.gov/pubmed/28880525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.7b00287
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