Bioenergetic restoration and neuroprotection after therapeutic targeting of mitoNEET: new mechanism of Pioglitazone following traumatic brain injury

Mitochondrial dysfunction is a pivotal event in many neurodegenerative disease states including traumatic brain injury (TBI) and spinal cord injury (SCI). One possible mechanism driving mitochondrial dysfunction is glutamate excitotoxicity leading to Ca(2+)-overload in neuronal or glial mitochondria...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Exp Neurol
Egile Nagusiak: Yonutas, Heather M., Hubbard, W. Brad, Pandya, Jignesh D., Vekaria, Hemendra J., Geldenhuys, Werner J., Sullivan, Patrick G.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7089834/
https://ncbi.nlm.nih.gov/pubmed/32057797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2020.113243
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