Bioenergetic restoration and neuroprotection after therapeutic targeting of mitoNEET: new mechanism of Pioglitazone following traumatic brain injury

Mitochondrial dysfunction is a pivotal event in many neurodegenerative disease states including traumatic brain injury (TBI) and spinal cord injury (SCI). One possible mechanism driving mitochondrial dysfunction is glutamate excitotoxicity leading to Ca(2+)-overload in neuronal or glial mitochondria...

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Bibliografiske detaljer
Udgivet i:Exp Neurol
Main Authors: Yonutas, Heather M., Hubbard, W. Brad, Pandya, Jignesh D., Vekaria, Hemendra J., Geldenhuys, Werner J., Sullivan, Patrick G.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7089834/
https://ncbi.nlm.nih.gov/pubmed/32057797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2020.113243
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