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4-Hydroxynonenal and 4-Oxononenal Differentially Bind to the Redox Sensor MitoNEET

MitoNEET is a CDGSH iron–sulfur protein that has been a target for drug development for diseases such as type-2 diabetes, cancer, and Parkinson’s disease. Functions proposed for mitoNEET are as a redox sensor and regulator of free iron in the mitochondria. We have investigated the reactivity of mito...

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Detaylı Bibliyografya
Yayımlandı:Chem Res Toxicol
Asıl Yazarlar: Arnett, Dayna, Quillin, Alexandria, Geldenhuys, Werner J., Menze, Michael A., Konkle, Mary
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7556333/
https://ncbi.nlm.nih.gov/pubmed/31117349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.9b00166
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