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Redox characterization of the FeS protein mitoNEET and impact of thiazolidinedione drug binding

MitoNEET is a small mitochondrial protein that has been identified recently as a target for the thiazolidinedione (TZD) class of diabetes drugs. MitoNEET also binds a unique 3His/1Cys-ligated [2Fe2S(2)] cluster. Here we use protein film voltammetry (PFV) as a means to probe the redox properties of M...

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Detalhes bibliográficos
Main Authors: Bak, Daniel W., Zuris, John A., Paddock, Mark L., Jennings, Patricia A., Elliott, Sean J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322619/
https://ncbi.nlm.nih.gov/pubmed/19791753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi9016445
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