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Conserved Hydrogen Bonding Networks of MitoNEET Tune FeS Cluster Binding and Structural Stability
While its biological function remains unclear, the 3-Cys, 1-His ligated human [2Fe-2S] cluster containing protein mitoNEET is of interest due to its interaction with the anti-diabetes drug pioglitazone. The mitoNEET [2Fe-2S] cluster demonstrates proton coupled-electron transfer (PCET) and marked clu...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3940166/ https://ncbi.nlm.nih.gov/pubmed/23758282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400540m |
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