Redox-dependent gating of VDAC by mitoNEET

MitoNEET is an outer mitochondrial membrane protein essential for sensing and regulation of iron and reactive oxygen species (ROS) homeostasis. It is a key player in multiple human maladies including diabetes, cancer, neurodegeneration, and Parkinson’s diseases. In healthy cells, mitoNEET receives i...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Lipper, Colin H., Stofleth, Jason T., Bai, Fang, Sohn, Yang-Sung, Roy, Susmita, Mittler, Ron, Nechushtai, Rachel, Onuchic, José N., Jennings, Patricia A.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2019
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6778226/
https://ncbi.nlm.nih.gov/pubmed/31527235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1908271116
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