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Interdomain communication revealed in the diabetes drug target mitoNEET

MitoNEET is a recently identified drug target for a commonly prescribed diabetes drug, Pioglitazone. It belongs to a previously uncharacterized ancient family of proteins for which the hallmark is the presence of a unique 39 amino acid CDGSH domain. In order to characterize the folding landscape of...

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Detalhes bibliográficos
Main Authors: Baxter, Elizabeth L., Jennings, Patricia A., Onuchic, José N.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069162/
https://ncbi.nlm.nih.gov/pubmed/21402934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1017604108
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