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Strand swapping regulates the iron-sulfur cluster in the diabetes drug target mitoNEET
MitoNEET is a recently identified diabetes drug target that coordinates a transferable 2Fe-2S cluster, and additionally contains an unusual strand swap. In this manuscript, we use a dual basin structure-based model to predict and characterize the folding and functionality of strand swapping in mitoN...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3277509/ https://ncbi.nlm.nih.gov/pubmed/22308404 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1116369109 |
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