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Interdomain communication revealed in the diabetes drug target mitoNEET
MitoNEET is a recently identified drug target for a commonly prescribed diabetes drug, Pioglitazone. It belongs to a previously uncharacterized ancient family of proteins for which the hallmark is the presence of a unique 39 amino acid CDGSH domain. In order to characterize the folding landscape of...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3069162/ https://ncbi.nlm.nih.gov/pubmed/21402934 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1017604108 |
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