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Identification of small molecules that bind to the mitochondrial protein mitoNEET

MitoNEET (CISD1) is a 2Fe-2S iron-sulfur cluster protein belonging to the zinc-finger protein family. Recently mitoNEET has been shown to be a major role player in the mitochondrial function associated with metabolic type diseases such as obesity and cancers. The anti-diabetic drug pioglitazone and...

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Detalhes bibliográficos
Publicado no:Bioorg Med Chem Lett
Main Authors: Geldenhuys, Werner J., Yonutas, Heather M., Morris, Daniel L., Sullivan, Patrick G., Darvesh, Altaf S., Leeper, Thomas C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482219/
https://ncbi.nlm.nih.gov/pubmed/27687671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2016.09.009
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