MitoNEET (CISD1) Knockout Mice Show Signs of Striatal Mitochondrial Dysfunction and a Parkinson’s Disease Phenotype

Mitochondrial dysfunction is thought to play a significant role in neurodegeneration observed in Parkinson’s disease (PD), yet the mechanisms underlying this pathology remain unclear. Here, we demonstrate that loss of mitoNEET (CISD1), an iron–sulfur containing protein that regulates mitochondrial b...

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Vydáno v:ACS Chem Neurosci
Hlavní autoři: Geldenhuys, Werner J., Benkovic, Stanley A., Lin, Li, Yonutas, Heather M., Crish, Samuel D., Sullivan, Patrick G., Darvesh, Altaf S., Brown, Candice M., Richardson, Jason R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5964979/
https://ncbi.nlm.nih.gov/pubmed/28880525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.7b00287
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