MitoNEET (CISD1) Knockout Mice Show Signs of Striatal Mitochondrial Dysfunction and a Parkinson’s Disease Phenotype

Mitochondrial dysfunction is thought to play a significant role in neurodegeneration observed in Parkinson’s disease (PD), yet the mechanisms underlying this pathology remain unclear. Here, we demonstrate that loss of mitoNEET (CISD1), an iron–sulfur containing protein that regulates mitochondrial b...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:ACS Chem Neurosci
Prif Awduron: Geldenhuys, Werner J., Benkovic, Stanley A., Lin, Li, Yonutas, Heather M., Crish, Samuel D., Sullivan, Patrick G., Darvesh, Altaf S., Brown, Candice M., Richardson, Jason R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5964979/
https://ncbi.nlm.nih.gov/pubmed/28880525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.7b00287
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg