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Guide-bound structures of an RNA-targeting A-cleaving CRISPR-Cas13a enzyme
CRISPR adaptive immune systems protect bacteria from infections by deploying CRISPR RNA (crRNA)-guided enzymes to recognize and cut foreign nucleic acids. Type VI-A CRISPR-Cas systems include the Cas13a enzyme, an RNA-activated ribonuclease (RNase) capable of crRNA processing and single-stranded RNA...
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| Publicado no: | Nat Struct Mol Biol |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5961731/ https://ncbi.nlm.nih.gov/pubmed/28892041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3466 |
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