Overexpression of the base excision repair NTHL1 glycosylase causes genomic instability and early cellular hallmarks of cancer

Base excision repair (BER), which is initiated by DNA N-glycosylase proteins, is the frontline for repairing potentially mutagenic DNA base damage. The NTHL1 glycosylase, which excises DNA base damage caused by reactive oxygen species, is thought to be a tumor suppressor. However, in addition to NTH...

全面介紹

Na minha lista:
書目詳細資料
發表在:Nucleic Acids Res
Main Authors: Limpose, Kristin L, Trego, Kelly S, Li, Zhentian, Leung, Sara W, Sarker, Altaf H, Shah, Jason A, Ramalingam, Suresh S, Werner, Erica M, Dynan, William S, Cooper, Priscilla K, Corbett, Anita H, Doetsch, Paul W
格式: Artigo
語言:Inglês
出版: Oxford University Press 2018
主題:
Genome Integrity, Repair and Replication
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5961185/
https://ncbi.nlm.nih.gov/pubmed/29522130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky162
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍