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p53 coordinates base excision repair to prevent genomic instability

DNA constantly undergoes chemical modification due to endogenous and exogenous mutagens. The DNA base excision repair (BER) pathway is the frontline mechanism handling the majority of these lesions, and primarily involves a DNA incision and subsequent resealing step. It is imperative that these proc...

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Detaylı Bibliyografya
Yayımlandı:Nucleic Acids Res
Asıl Yazarlar: Poletto, Mattia, Legrand, Arnaud J., Fletcher, Sally C., Dianov, Grigory L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4838360/
https://ncbi.nlm.nih.gov/pubmed/26773055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw015
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